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Piperonyl butoxide : ウィキペディア英語版
Piperonyl butoxide

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Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is a waxy white solid. It is a synergist. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone.〔(National Pesticide Information Center - Piperonyl Butoxide General Fact Sheet )〕 It is a semisynthetic derivative of safrole.〔Robert L. Metcalf "Insect Control" in Ullmann’s Encyclopedia of Industrial Chemistry" Wiley-VCH, Weinheim, 2002. 〕
==History==
PBO was developed in the late 1930s and early 1940s to enhance the performance of the naturally derived insecticide pyrethrum. Pyrethrum is and was an important insecticide against mosquitoes and other disease-carrying vectors, thereby providing public health benefits, e.g., preventing malaria. Although exhibiting little intrinsic insecticidal activity of its own, PBO increases the effectiveness of pyrethrins and were thus are called synergists. PBO was first patented in 1947 in the US by Herman Wachs.〔Glynne-Jones, D. (1998). History of PBO In "PBO—The Insecticide Synergist" (D. Glynne Jones, ed.). Academic Press, San Diego.〕

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